Bleeding disorders can be inherited (genetic) or can occur later in life (acquired). Inherited (genetic) bleeding disorders are passed from parents to children through a gene. Inherited bleeding disorders can occur when a chromosome containing an altered or defective clotting factor is passed from parent to child. When people think of an inherited bleeding disorder, they usually think of hemophilia
, which is usually caused by a missing or altered gene for factor VIII or factor IX. Hemophilia is passed on from parent to child through one of the sex-link chromosomes. Other bleeding disorders, including von Willebrand's
disease are passed from parent to child by way of the non-sex-linked chromosomes (known as autosomes).